Presentation at CEO Summit 2018

Patrick Boisseau, Deputy Head of Division, European Affairs at CEA-LETI and ... Read more

Health EU – Human avatars to prevent and cure diseases

Imagine a revolution in personalized healthcare and disease prevention system in Europe, based on human avatars of healthy individuals and patients for the prevention, interception and cure of disease.

Nothing less is the aim of Health EU (healthy you!), an advanced FET Flagship multidisciplinary research initiative in Europe aiming for a paradigm shift to healthcare and for a future sustainable healthcare system.
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A revolution in human model development is now possible with Health EU by leveraging data from omics analyses, medical and imaging data, environmental and life style big data that are continuously updated by a multitude of biosensors at an unprecedented scale. With these complex data sets, first of their kind(s) human avatars will be built that can be personalised and used to prevent and cure each one’s own disease(s). Health EU will exploit most advanced organ-on-chip, smart nanosensor technologies and nanomedicine techniques to realise, validate and use such personalized human avatars in order to create a revolution in healthcare.

Health EU will boost European innovation and create disruptive advances related to big data analytics, smart micro/nano-systems, nanomedicine and new healthcare services and safer and more effective drugs. It will directly contribute to standards for privacy and security of healthcare data, jointly driven by technology and context. Health EU FET Flagship will provide a truly sustainable approach to healthcare and a better Quality of Life to European citizens.

Our Story

The Health EU FET Flagship is a star Flagship initiative born as a result of merging revolutionary ideas about the future of healthcare and leading European research groups from:
  • the past FET Flagship finalist ‘Guardian Angels for a Smarter Life’, and related most advanced edge of the cloud and Internet of Things sensor and smart system integration technology platforms, centered at IMEC, CEA-LETI and Fraunhofer
  • the Organ-on-Chip Flagship initiative led by the Dutch hDMT (Institute for human Organ and Disease Model Technologies) and its European network
  • a large number of groups and leaders formerly being involved in the Flagship Expression of Interest ‘The Future of Health Care: deep data, smart sensors, virtual patients and the Internet-of-Humans
  • the Nanomedicine European Technology platform
  • key partners from the Flag-Era Convergence project
  • many other European universities, research institutes, hospitals, industries and networks that decided to integrate and support Health EU

Partners

The following partners will work together for a year-long coordination action, preparing the final Flagship Initiative.
École Polytechnique Fédérale de Lausanne (EPFL)
Switzerland
Kamiar Aminian, Jürgen Brugger, Giovanni De Micheli, Bart Deplancke, Christian Enz, Adrian Ionescu, Stéphanie Lacour, Matthias Lütolf, Marco Mattavelli, Philippe Renaud, Ali H. Sayed, Anja Skrivervik, Jean-Philippe Thiran
Charité – Universitätsmedizin Berlin
Germany
Volkmar Falk, Titus Kuehne, Alexander Meyer
Kungliga Tekniska Högskolan (KTH)
Sweden
Mikael Ostling, Matthias Uhlen, Ana Rusu
Fraunhofer-Gesellschaft
Germany
Anja Hennemuth, Christine Kallmayer, Peter Ramm, Andreas Schneider
Weizmann Institute of Science
Israel
Eran Segal
Stichting IMEC Nederland
The Netherlands
Sywert Brongersma
SINTEF
Norway
Thomas Langø
Italian National Research Council (CNR)
Italy
Luca Businaro, Pietro Siciliano
Instituto de Salud Carlos III
Spain
Fernando Martin Sanchez
Bosch R & D
Germany
Franz Lärmer
Katholieke Universiteit Leuven
Belgium
Georges Gielen
Université catholique de Louvain
Belgium
Denis Fladre, Jean-Pierre Raskin
Swiss Institute of Bioinformatics
Switzerland
Jerome.Dauvillier@sib.swiss
Agenzia nazionale per le nuove tecnologie, l'energia e lo sviluppo economico sostenibile (ENEA)
Italy
Girolamo Di Francia, Saverio De Vito
Tyndall National Institute
Ireland
Paul Galvin, David Wilson
Commissariat à l’énergie atomique et aux énergies alternatives (CEA-LETI)
France
Patrick Boisseau, Thomas Ernst
human Organ and Disease Model Technologies (hDMT)
The Netherlands
Albert van den Berg, Janny van den Eijnden, Christine Mummery
University of Twente
The Netherlands
Albert van den Berg
Eidgenössische Technische Hochschule Zürich (ETHZ)
Switzerland
Luca Benini, Joachim Buhmann, Stephen Ferguson, Andreas Hierlemann, Christopher Hierold, Walter Karlen, Bradley Nelson, Lothar Thiele
Biocluster Genopôle
France
Denis Gauvreau
imec-vzw
Belgium
Chris van Hoof
Consorzio Nazionale Interuniversitario per la Nanoelettronica (IU.NET)
Italy
Enrico Sangiorgi, Luca Selmi
SCIPROM Sàrl
Switzerland
Kirsten Leufgen
Technical University of Denmark
Denmark
Jan Madsen
Rheinisch-Westfälische Technische Hochschule Aachen
Germany
Max Lemme
IMT Bucharest
Romania
Carmen Moldovan, Raluca Muller
National Center for Scientific Research DEMOKRITOS
Greece
Athanasios Dimoulas
Tel Aviv University
Israel
Dan Peer
Imperial College
UK
Marisa Miraldo
Queen Mary University London
UK
Anthony Mathur, Sheik Dowlut
Infineon Technologies AG
Germany
Knut Hufeld, Reinhard Pufall
HITS gGmbH
Germany
Martin Golebiewski, Wolfgang Müller
Centre Hospitalier Universitaire Vaudois
Switzerland
Jocelyne Bloch Pasche, Salah D. Qanadli, Piergiorgio Tozzi
Gustave Roussy Institute
France
Alexander M.M. Eggermont
Italian Institute for Genomic Medicine
Italy
Ruggero de Maria
Télécom SudParis
France
Marius Preda
VTT - Technical Research Centre of Finland
Finland
Ari Alastalo, Veikko Ikonen, Eija Kaasinen
Universität Zürich
Switzerland
Giacomo Indiveri
Philips NV
The Netherlands
Wim Crooijmans
University Leipzig
Germany
Thomas Neumuth
University Medical Center Groningen
The Netherlands
Cisca Wijmenga
Alliance Against Cancer
Italy
Myriam Alkalay
Max Planck Institute (MPI) of Microstructure Physics
Germany
Eberhard Bodenschatz, Detlef Lohse, Stuart Parkin
Istituto Superiore Mario Boella sulle Tecnologie dell' Informazione e delle Telecomunicazioni
Italy
Paolo Vergori
Catalan Institute of Nanoscience and Nanotechnology
Spain
José Antonio Garrido
Norwegian University of Science and Technology
Norway
Frank Lindseth
INP Grenoble
France
Francis Balestra
CHU Grenoble
France
Alexandre Moreau-Gaudry
LUMC
The Netherlands
Christine Mummery
Institute of Electronics and Computer Science
Latvia
Modris Greitans
CNRS
France
Dominique Collard, Eric McAdams
Eberhard Karls Universität Tübingen
Germany
Peter Loskill
Otto von Guericke University Magdeburg
Germany
Steffen Oeltze-Jafra, Hans-Jochen Heinze, Hermann Hinrichs, Oliver Speck, Emrah Düzel
University of Zaragoza
Spain
Ignacio Ochoa, Manuel Doblaré; Luis Fernandez
National Technical University of Athens
Greece
Ioanna Zergioti, Apostolos Klinakis, Dimitris Tsoukalas, Yannis Raptis
Jena University Hospital
Germany
Alexander Mosig, Martin Raasch
University of Surrey
United Kingdom
Christian Heiss, Helen Griffiths, A. Gawer
Bar Ilan University
Israel
Aharon Gedanken, Jean-Paul Lellouche
EMPA
Switzerland
Peter Wick
University of Brighton
United Kingdom
Matteo Santin
University of Groningen
The Netherlands
Reinoud Gosens; Loes Kistemaker
Università Campus Bio-Medico di Roma
Italy
Marco Santonico, Giorgio Pennazza
Hellenic Pasteur Institute, Athens
Greece
Rebecca Matsas
TU Wien & Vienna University of Technologoy
Austria
Clemens Heitzinger & Peter Ertl, Mario Rothbauer
Dept. Electronic Engineering University of Roma Tor Vergata
Italy
Eugenio Martinelli; Arianna Mencattini
University of Cagliari
Italy
Luigi Raffo
NMI Natural and Medical Sciences Institute
Germany
Udo Kraushaar
University of Twente
The Netherlands
Andries van der Meer
Catholic University of Croatia
Croatia
Anto Čartolovni, Hrvoje Meštrić
EPOS-Iasis, R&D and University of Cyprus
Cyprus
Andreani D. Odysseos, Loizos Economides
University of Bern
Switzerland
Stephen Leib, Alban Ramette, Denis Grandgirard, Thomas Geiser, Olivier Guenat
Université Paris Sud
France
Patrick Couvreur, Elie Lefeuvre
Tallinn University of Technology
Estonia
Mart Min
University of Oslo
Norway
Stefan Krauss
Politehnica University Bucharest
Romania
Gheorghe Brezeanu
Nalecz Institute of Biocybernetics and Biomedical Engineering Polish Academy of Sciences
Poland
Adam Liebert
Merck
Germany
Charles Massin
Technical University of Munich (TUM)
Germany
Sandra Hirche, Bjoern Menze, Nassir Navab, Daniel Cremers
CSEM
Switzerland
John Farserotu
Bayer
Germany
Lars Küpfer
Université Lyon 1 Claude Bernard
France
Abdelhamid Errachid El Salhi Michel Ovize
Centre of Excellence in Body-On-Chip Research (CoEBoC
Finland
Mari Pekkanen-Mattila
Radboud Universitair Medical Center & ParkinsonNet
The Netherlands
Bas Bloem
Institute for Experimental Molecular Imaging, UK Aachen
Germany
Fabian Kiessling
IBM Zurich
Switzerland
Jonas Weiss
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
Daniel Popa, Flurin Udrea
Over 100 partners from more than 20 EU countries already confirmed their interest in participating in the final Health EU Flagship Initiative.
The Health EU Stakeholder Forum will play a crucial role in shaping our Flagship vision and its implementation by considering the interactive involvement of big industries, SMEs, startups, patient organizations, regulatory bodies, etc.

The Chairs of the Health-EU Stakeholder Forum are Prof. Christofer Hierold (ETHZ) and Dr. Franz Lärmer (VP Corporate Research and Advanced Engineering - Robert Bosch GmbH, Germany).

News and Events

Presentation at CEO Summit 2018

Patrick Boisseau, Deputy Head of Division, European Affairs at CEA-LETI and member of the Health EU steering board, presented the Health EU Flagship approach today at the CEO Summit 2018 in Brussels. The audience composed of 60+ industrial leaders in medtech and diagnostics companies was delighted about this foresight looking lecture. Some interesting questions about ethical and societal issues related to avatars or “when will it be available” gave rise for discussion and some very positive feedback was received during the coffee breaks.

Health EU at ETPN 2018, Berlin

Patrick Boisseau, Deputy Head of Division, European Affairs at CEA-LETI and Chairman of the ETPN, presented Health EU Flagship approach at ETPN 2018, Berlin, Germany, in a talk entitled: ''Human avatars to prevent and cure diseases Health EU vision for a sustainable future of the European healthcare'', attracting significant support and high interest from the audience for the Health EU Flagship.

Two EPFL projects make it to the second round

Both of the EPFL projects that applied for the European Commission’s FET Flagship programme have successfully cleared the first hurdle. These projects are the Time Machine, headed by Frédéric Kaplan at the Digital Humanities Laboratory, and Health EU, run by Adrian Ionescu at the Nanoelectronic Devices Laboratory (Nanolab). If selected, they will receive one billion euros over ten years as part of the European Commission’s ambitious funding programme.

With Health EU, everyone will one day have their own medical avatar – a virtual replica of themselves featuring their own personal data – that could improve the way their health is managed and the treatments they are given. This international project, led by a consortium headed by EPFL and the University of Twente, aims to achieve enhanced disease prevention, early diagnosis, more accurate monitoring and customized, targeted administration of medicines and treatments, especially for increasingly common diseases such as cancer and cardiovascular, chronic and neurodegenerative disorders.

The Time Machine is based on the Venice Time Machine (VTM), a project that started in 2012 and served as a proof of concept. The VTM aimed to build a multidimensional model of the city that spans the past millennium, using millions of historical documents stored in a variety of formats. After five years, the project team has scanned 190,000 records from the Venice State Archive along with 720,000 photographs and 3,000 books on Venice’s history. The objective of the Time Machine is to replicate the VTM across Europe. It will create a large-scale simulator for mapping 2,000 years of European history and turning the huge archives and sizeable museum collections into one big digital information system.

A total of 33 projects from universities across Europe have applied for the programme, which is intended to support future and emerging technologies (FET). Only 17 of them – just over half – were selected for the second round, scheduled to end on 18 September 2018.EPFL also plays a key role in a third project in the running for a FET Flagship, Robotics Flagship, which made it through to the second round as well.

The full EPFL press release including more information about the proposals you can find here.

Outstanding support for Health EU

Professor Ben Feringa, who won the 2016 Nobel Prize in chemistry for the development of molecular machines, expresses his appreciation of the Health EU proposal: “This is a very ambitious programme that combines modern science and technology to create new opportunities for the future of healthcare and keep it affordable.”

Professor Feringa is a pioneer in the field of molecular engines, catalysis and smart medication.

Health EU proposal invited for next stage of competition!

Excellent news: The European Commission has invited the Health EU proposal to enter the next stage of competition for the selection of new EU Flagships for Future and Emerging Technologies.

We are thrilled to be one step closer to the realisation of our dream: a revolution in personalized healthcare and disease prevention system in Europe, based on human avatars of healthy individuals and patients for the prevention, interception and cure of disease.

Health EU press release launched by EPFL

The Health EU coordinating organisation, Ecole polytechnique fédérale de Lausanne (EPFL) has published today a press release presenting the project. Enjoy reading!

Health EU phase 1 proposal submitted!

The Health EU phase 1 proposal has been submitted successfully yesterday!

It is one of 33 proposals submitted to the topic FETFLAG-01-2018: Preparatory Actions for new FET Flagships.

The results for phase 1 of the evaluation should be known in 3 months from now.

Website published!

The Health EU website is online! Further information and updates will follow after the Christmas Break. Happy holidays!

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