Presentation at CEO Summit 2018

Patrick Boisseau, Deputy Head of Division, European Affairs at CEA-LETI and ... Read more

Health EU – Human avatars to prevent and cure diseases

Imagine a revolution in personalized healthcare and disease prevention system in Europe, based on human avatars of healthy individuals and patients for the prevention, interception and cure of disease.

Nothing less is the aim of Health EU (healthy you!), an advanced FET Flagship multidisciplinary research initiative in Europe aiming for a paradigm shift to healthcare and for a future sustainable healthcare system.
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A revolution in human model development is now possible with Health EU by leveraging data from omics analyses, medical and imaging data, environmental and life style big data that are continuously updated by a multitude of biosensors at an unprecedented scale. With these complex data sets, first of their kind(s) human avatars will be built that can be personalised and used to prevent and cure each one’s own disease(s). Health EU will exploit most advanced organ-on-chip, smart nanosensor technologies and nanomedicine techniques to realise, validate and use such personalized human avatars in order to create a revolution in healthcare.

Health EU will boost European innovation and create disruptive advances related to big data analytics, smart micro/nano-systems, nanomedicine and new healthcare services and safer and more effective drugs. It will directly contribute to standards for privacy and security of healthcare data, jointly driven by technology and context. Health EU FET Flagship will provide a truly sustainable approach to healthcare and a better Quality of Life to European citizens.

Our Story

The Health EU FET Flagship is a star Flagship initiative born as a result of merging revolutionary ideas about the future of healthcare and leading European research groups from:
  • the past FET Flagship finalist ‘Guardian Angels for a Smarter Life’, and related most advanced edge of the cloud and Internet of Things sensor and smart system integration technology platforms, centered at IMEC, CEA-LETI and Fraunhofer
  • the Organ-on-Chip Flagship initiative led by the Dutch hDMT (Institute for human Organ and Disease Model Technologies) and its European network
  • a large number of groups and leaders formerly being involved in the Flagship Expression of Interest ‘The Future of Health Care: deep data, smart sensors, virtual patients and the Internet-of-Humans
  • the Nanomedicine European Technology platform
  • key partners from the Flag-Era Convergence project
  • many other European universities, research institutes, hospitals, industries and networks that decided to integrate and support Health EU

Partners

The following partners will work together for a year-long coordination action, preparing the final Flagship Initiative.
École Polytechnique Fédérale de Lausanne (EPFL)
Switzerland
Kamiar Aminian, Jürgen Brugger, Giovanni De Micheli, Bart Deplancke, Christian Enz, Adrian Ionescu, Stéphanie Lacour, Matthias Lütolf, Marco Mattavelli, Philippe Renaud, Ali H. Sayed, Anja Skrivervik, Jean-Philippe Thiran
Charité – Universitätsmedizin Berlin
Germany
Volkmar Falk, Titus Kuehne, Alexander Meyer
Kungliga Tekniska Högskolan (KTH)
Sweden
Mikael Ostling, Matthias Uhlen
Fraunhofer-Gesellschaft
Germany
Anja Hennemuth, Christine Kallmayer, Peter Loskill, Peter Ramm, Andreas Schneider
Weizmann Institute of Science
Israel
Eran Segal
Stichting IMEC Nederland
The Netherlands
Sywert Brongersma
SINTEF
Norway
Thomas Langø
Italian National Research Council (CNR)
Italy
Luca Businaro, Pietro Siciliano
Instituto de Salud Carlos III
Spain
Fernando Martin Sanchez
Bosch R & D
Germany
Franz Lärmer
Katholieke Universiteit Leuven
Belgium
Georges Gielen
Université catholique de Louvain
Belgium
Denis Fladre, Jean-Pierre Raskin
Swiss Institute of Bioinformatics
Switzerland
Ioannis Xenarios
Agenzia nazionale per le nuove tecnologie, l'energia e lo sviluppo economico sostenibile (ENEA)
Italy
Girolamo Di Francia, Saverio De Vito
Tyndall National Institute
Ireland
Paul Galvin, David Wilson
Commissariat à l’énergie atomique et aux énergies alternatives (CEA-LETI)
France
Patrick Boisseau, Thomas Ernst
human Organ and Disease Model Technologies (hDMT)
The Netherlands
Albert van den Berg, Janny van den Eijnden, Christine Mummery
University of Twente
The Netherlands
Albert van den Berg
Eidgenössische Technische Hochschule Zürich (ETHZ)
Switzerland
Luca Benini, Joachim Buhmann, Stephen Ferguson, Andreas Hierlemann, Christopher Hierold, Walter Karlen, Bradley Nelson, Lothar Thiele
Biocluster Genopôle
France
Denis Gauvreau
imec-vzw
Belgium
Chris van Hoof
Consorzio Nazionale Interuniversitario per la Nanoelettronica (IU.NET)
Italy
Enrico Sangiorgi, Luca Selmi
SCIPROM Sàrl
Switzerland
Kirsten Leufgen
Technical University of Denmark
Denmark
Jan Madsen
Rheinisch-Westfälische Technische Hochschule Aachen
Germany
Max Lemme
IMT Bucharest
Romania
Carmen Moldovan, Raluca Muller
National Center for Scientific Research DEMOKRITOS
Greece
Athanasios Dimoulas
Tel Aviv University
Israel
Dan Peer
Imperial College
UK
Marisa Miraldo
Queen Mary University London
UK
Anthony Mathur
Infineon Technologies AG
Germany
Knut Hufeld, Reinhard Pufall
HITS gGmbH
Germany
Martin Golebiewski, Wolfgang Müller
Centre Hospitalier Universitaire Vaudois
Switzerland
Jocelyne Bloch Pasche, Salah D. Qanadli, Piergiorgio Tozzi
Gustave Roussy Institute
France
Alexander M.M. Eggermont
Italian Institute for Genomic Medicine
Italy
Ruggero de Maria
Télécom SudParis
France
Marius Preda
VTT - Technical Research Centre of Finland
Finland
Ari Alastalo, Veikko Ikonen, Eija Kaasinen
Universität Zürich
Switzerland
Giacomo Indiveri
Philips NV
The Netherlands
Wim Crooijmans
University Leipzig
Germany
Steffen Oeltze-Jafra
University Medical Center Groningen
The Netherlands
Cisca Wijmenga
Alliance Against Cancer
Italy
Myriam Alkalay
Max Planck Institute (MPI) of Microstructure Physics
Germany
Eberhard Bodenschatz, Detlef Lohse, Stuart Parkin
Istituto Superiore Mario Boella sulle Tecnologie dell' Informazione e delle Telecomunicazioni
Italy
Paolo Vergori
Catalan Institute of Nanoscience and Nanotechnology
Spain
José Antonio Garrido
Norwegian University of Science and Technology
Norway
Frank Lindseth
INP Grenoble
France
Francis Balestra
CHU Grenoble
France
Alexandre Moreau-Gaudry
LUMC
The Netherlands
Christine Mummery
Institute of Electronics and Computer Science
Latvia
Modris Greitans
CNRS
France
Dominique Collard
These partners already confirmed their interest in participating in the final Flagship Initiative.
Name of the organisationPerson of contactCountry
3D PLUS SASPascal CoudercFrance
AlveoliX AGOlivier Guenat, Nina Hobi, Janick StuckiSwitzerland
AMOMax LemmeGermany
Bar Ilan UniversityAharon Gedanken, Jean-Paul Lellouche, Ilana PerelshteinIsrael
BiovistaAndreas Persidis, Eftychia LekkaGreece
Catholic University of CroatiaAnto Čartolovni, Hrvoje MeštrićCroatia
CEA GrenobleXavier Gidrol, Nathalie Picollet-d’HahanFrance
CIMUS Research InstituteJosé Crecente CampoSpain
CNRS Toulouse, LAASLiviu Nicu, Christophe Vieu, Daniela Dragomirescu, Bernard Legrand, Aurélien Bancaud, Laurent PerezFrance
Delft University of TechnologyPasqualina M. Sarro, Wouter Serdijn, Michiel Pertijs, Geert LeusThe Netherlands
Delft University of TechnologySorin CotofanaThe Netherlands
Democritus University of Thrace, GreeceIoannis Karafyllidis, Georgios SirakoulisGreece
Department of Pulmonary Medicine, University Hospital, Unversity of Bern, SwitzerlandThomas GeiserSwitzerland
Dept. Electronic Engineering University of Roma Tor VergataEugenio Martinelli; Arianna MencattiniItaly
Diavita LtdDimiter DimitrovBulgaria
EMPA, Swiss Federal Laboratories for Material Science and TechnologyPeter Wick, Tina Bürki-Thurnherr, Inge HerrmannSwitzerland
EPOS-Iasis, R&D and University of CyprusAndreani D. Odysseos, Loizos EconomidesCyprus
Erasmus University Medical Center RotterdamPeter van der Spek, John Martens, Steven Kushner The Netherlands
eResult S.r.l.Antonino Ferrara, Massimo Pistoia, Gianfranco BorrelliItaly
FHNW - University of Applied Sciences and Arts Northwestern Switzerland, Institute for Medical and Analytical Technologies Maurizio Gullo, David Hradetzky, Erik SchkommodauSwitzerland
HealthskoutsKoen KasBelgium
Hellenic Oncology Research Group (HORG)Vassilis GeorgouliasGreece
Hellenic Pasteur Institute, AthensRebecca Matsas, Era TaoufikGreece
INRA - Human Nutrition UnitSergio Polakof, Estelle Pujos-Guillot France
Institute for Infectious Diseases, University of Bern, SwitzerlandStephen Leib, Alban Ramette, Denis GrandgirardSwitzerland
Institute of Nanoscience and Nanotewchnology (INN) at NCSR DemokritosAndroula NassiopoulouGreece
Jena University HospitalAlexander Mosig, Martin RaaschGermany
National Technical University of AthensIoanna Zergioti, Apostolos Klinakis, Dimitris Tsoukalas, Yannis RaptisGreece
NMI Natural and Medical Sciences InstituteUdo KraushaarGermany
RIKILT-Wageningen University & ResearchMeike van der Zande, Ad PeijnenburgThe Netherlands
SanofiHartmut RuettenGermany
Tissue Click LtdGary Phillips, Anna GuildfordUnited Kingdom
TU WienClemens HeitzingerAustria
University of Applied Sciences and Arts Western SwitzerlandMaurizio CaonSwitzerland
University of CoimbraLino Ferreira, Luis EstroncaPortugal
University of GenevaGerrit Borchard Switzerland
University of GroningenReinoud Gosens; Loes KistemakerThe Netherlands
University of LuxemburgJens Schwamborn, Philippe Lucarelli, Paul Wilmes, Cedric Christian LacnyLuxembourg
University of Napoli Federico II, Department of Electrical Engineering and Information TechnologyAntonio Pescapè, Giuseppe AcetoItaly
University of PisaGuiseppe Barillaro, S. MarianiItaly
University of SurreyChristian Heiss, Helen GriffithsUnited Kingdom
University of TrentoFabio Ledda; Alessandro QuattroneItaly
University of ZaragozaIgnacio Ochoa, Manuel Doblaré; Luis FernandezSpain
Università Campus Bio-Medico di RomaMarco Santonico, Giorgio PennazzaItaly
Università di BresciaVittorio FerrariItaly
Vienna University of TechnologyPeter Ertl, Mario RothbauerAustria
Wageningen UniversityHans Bouwmeester, John van der OostThe Netherlands
The Health EU Stakeholder Forum will play a crucial role in shaping our Flagship vision and its implementation by considering the interactive involvement of big industries, SMEs, startups, patient organizations, regulatory bodies, etc.

The Chairs of the Health-EU Stakeholder Forum are Prof. Christofer Hierold (ETHZ) and Dr. Franz Lärmer (VP Corporate Research and Advanced Engineering - Robert Bosch GmbH, Germany).

The following stakeholders have already confirmed their participation.
Name of the organisationPerson of contactCountry
AbbVieThomas JahnGermany
AlfaBetaNetLucio AnnunziatoItaly
Bioanalytic MünsterKlaus-Michael WeltringGermany
Bosch BKKFranz LaermerGermany
CACHET Jakob E. Bardram, Professor and DirectorDenmark
CEDEO SASLeonardo Chiariglione Italy
Corti Michael R. Boesen, PhD, Co-founder and VP Special ProjectsDenmark
CPH Health CHCHenning LangbergDenmark
DDS DiagnosticDana StanRomania
Dr. SchärOmbretta PolenghiItaly
Dutch Heart FoundationRebecca Abma-SchoutenThe Netherlands
EGANCees Smit, Cor OosterwijkThe Netherlands
EIT-HealthJan-Philipp BeckGermany
Eriksholm Research Center (part of Oticon)Uwe Hermann, DirectorDenmark
Eriksholm Research CentreUwe Andreas HermannDenmark
European Federation of Neurological Associations (EFNA)Cathalijne van DoorneBelgium
European Federation of Pharmaceutical Industries and Associations (EFPIA)Magda ChlebusBelgium
European Lung Foundation (ELF)Emma Thompson, Isabel SairavaUnited Kingdom
Fondazioen DonGnocchi OnlusFurio GramaticaItaly
greenTEG AGWulf GlatzSwitzerland
Helmholtz Inst for Pharma scienceClaus-Michael LehrGermany
InSphero AGOlivier Frey, Jan LichtenbergSwitzerland
IST AGMirko LehmannSwitzerland
JanssenRachel AdamsUnited Kingdom
LundbeckKenneth ThistrupDenmark
MaxWell BiosystemsUrs Frey, Michele FiscellaSwitzerland
Medicines Evaluation Board (the Netherlands)Jan Willem van der LaanThe Netherlands
MedTronicIves BayonFrance
MicronitRonny van 't OeverThe Netherlands
Microsoft DenmarkKim IbfeltDenmark
MinacNedRonny van ‘t OeverThe Netherlands
NC3RsSam JacksonUnited Kingdom
Neurescue Habib Frost, Founder and CEODenmark
Nordic.AILisa MallnerDenmark
NovartisKlaus SeuwenSwitzerland
NXP SemiconductorsRadu SurdeanuThe Netherlands
PfizerMark Soued The Netherlands
PhilipsSieger SwavingThe Netherlands
Praxis pharmaceuticalsEusebio GainzaFrance
S.C. Telemedica S.R LMioara RaduRomania
ST MicroelectronicsG. Desoli, Rolandi Canegallo, A. Cremonesi, Sabina Conoci
Wyss Center for Bio and NeuroengineeringTracy LaabsSwitzerland
XsensioEsmeralda MegallySwitzerland
Zilveren Kruis AchmeaAnja MoonenThe Netherlands

Support Health EU!

If you wish to be part of the CSA FETFLAG (Call : H2020-FETFLAG-2018-2020) Health EU Project or just to manifest your support to our idea, don't hesitate to write us!

News and Events

Presentation at CEO Summit 2018

Patrick Boisseau, Deputy Head of Division, European Affairs at CEA-LETI and member of the Health EU steering board, presented the Health EU Flagship approach today at the CEO Summit 2018 in Brussels. The audience composed of 60+ industrial leaders in medtech and diagnostics companies was delighted about this foresight looking lecture. Some interesting questions about ethical and societal issues related to avatars or “when will it be available” gave rise for discussion and some very positive feedback was received during the coffee breaks.

Health EU at ETPN 2018, Berlin

Patrick Boisseau, Deputy Head of Division, European Affairs at CEA-LETI and Chairman of the ETPN, presented Health EU Flagship approach at ETPN 2018, Berlin, Germany, in a talk entitled: ''Human avatars to prevent and cure diseases Health EU vision for a sustainable future of the European healthcare'', attracting significant support and high interest from the audience for the Health EU Flagship.

Two EPFL projects make it to the second round

Both of the EPFL projects that applied for the European Commission’s FET Flagship programme have successfully cleared the first hurdle. These projects are the Time Machine, headed by Frédéric Kaplan at the Digital Humanities Laboratory, and Health EU, run by Adrian Ionescu at the Nanoelectronic Devices Laboratory (Nanolab). If selected, they will receive one billion euros over ten years as part of the European Commission’s ambitious funding programme.

With Health EU, everyone will one day have their own medical avatar – a virtual replica of themselves featuring their own personal data – that could improve the way their health is managed and the treatments they are given. This international project, led by a consortium headed by EPFL and the University of Twente, aims to achieve enhanced disease prevention, early diagnosis, more accurate monitoring and customized, targeted administration of medicines and treatments, especially for increasingly common diseases such as cancer and cardiovascular, chronic and neurodegenerative disorders.

The Time Machine is based on the Venice Time Machine (VTM), a project that started in 2012 and served as a proof of concept. The VTM aimed to build a multidimensional model of the city that spans the past millennium, using millions of historical documents stored in a variety of formats. After five years, the project team has scanned 190,000 records from the Venice State Archive along with 720,000 photographs and 3,000 books on Venice’s history. The objective of the Time Machine is to replicate the VTM across Europe. It will create a large-scale simulator for mapping 2,000 years of European history and turning the huge archives and sizeable museum collections into one big digital information system.

A total of 33 projects from universities across Europe have applied for the programme, which is intended to support future and emerging technologies (FET). Only 17 of them – just over half – were selected for the second round, scheduled to end on 18 September 2018.EPFL also plays a key role in a third project in the running for a FET Flagship, Robotics Flagship, which made it through to the second round as well.

The full EPFL press release including more information about the proposals you can find here.

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